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Traditional Fermentation

Abbott has been developing, producing and marketing FDA-approved fermented drug products for well over 50 years. We have become the world’s leading supplier of various fermentation products including erythromycin.

We have been offering custom fermentation development and cGMP production services to partners for over a decade. We are truly one of the world's leaders in large scale fermentation technology. Come visit our facilities and you'll see why.

Organisms

Abbott has fermentation experience with the following types of organisms:

  • Actinomycetes
  • Molds
  • Bacteria
  • Yeast

Product Recovery

Abbott has full cGMP product recovery and purification capabilities including:

  • Cell homogenization
  • Centrifugation
  • Micro/Ultrafiltration
  • Chromatography
  • Distillation
  • Evaporation
  • Drying
  • Lyophillization
  • Solvent extraction
  • Reverse osmosis
  • Membrane filtration
  • Mixing
  • Crystallization
  • Blending
  • Granulation

Production Experience

Abbott has manufactured the following types of fermented products under various cGMP requirements:

  • Antibiotics
  • Recombinant proteins
  • Enzymes
  • Specialty chemicals
  • Biotransformations
  • Microbial cells
  • Mild pathogens

 

cGMP Multi-Use Facilities
Various sizes of fermentors are available
for the production of conventional and recombinant organisms. Fermentor sizes include shake flask to:
 

Pilot Plant:
40 liters
175 liters
500 liters
850 liters

  Semiworks:
2,000 liters
6,000 liters
18,000 liters
40,000 liters
  Commercial:
60,000 liters
110,000 liters
 

 

 

 

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